Analysis and Modeling of Neural Systems by George L. Gerstein (auth.), Frank H. Eeckman (eds.)

By George L. Gerstein (auth.), Frank H. Eeckman (eds.)

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6 mm. Figures 3D and 3E show the V2 projection focus centered in the field of view of frame 2. Figure 3D also shows a region, at the VIN2 border, between the stimulation and projection signal regions with no detectable signal. As is especially obvious in the grey-scale rendition, there is also a subsidiary focus roughly lateral to the main V2 focus. , 1973). In this experiment, we made a direct comparison between the position of the optical pattern with cytochrome oxidase sections processed from the same animal.

The stimulus train consisted of three biphasic pulses, (80 ~A in B, 40 ~A in C) with a 25 rnsec interpulse spacing delivered through 150 Kohm tungsten microelectrodes. As seen from the amplitudes of the characteristic three peaks of the cortical response to stimulation and indicated in panel A, there is a localized excited region around the stimulus site in panel B and a pair of foci in extrastriate cortex in Panel C. {/{<~

To complete the graphical representation we indicate, with the curve labeled S = 0, the values of V and S where, according to Eqn. 3, the growth rate of S balances its decay; above the curve, S is increasing, and below it, decreasing. This curve is called the S-nullcline. As an application of this representation, consider our model for bursting in the ,8-cell and suppose that the calcium removal rate kCa is glucose-sensitive (say, increasing with glucose). This parameter appears only in the equation for the slow variable, Eqn.

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